The Paterson Institute for Cancer Research is a leading cancer research institute within The University of Manchester, core funded by Cancer Research UK, the largest independent cancer research organisation in the world.
Research spans the whole spectrum of cancer research, from programmes investigating the molecular and cellular basis of cancer, to those focussed on translational research and the development of therapeutics.
Inhibiting EGF Receptor or SRC Family Kinase Signaling Overcomes BRAF Inhibitor Resistance in Melanoma.
Girotti MR, Pedersen M, Sanchez-Laorden B, Viros A, Turajlic S, Niculescu-Duvaz D, Zambon A, Sinclair J, Hayes A, Gore M, Lorigan P, Springer C, Larkin J, Jorgensen C, Marais R.
Cancer Discov. 2013 Feb;3(2):158-67. doi: 10.1158/2159-8290.CD-12-0386. Epub 2012 Dec 14.
PMID: 23242808 [PubMed - in process]
Sensitisation of c-MYC-induced B-lymphoma cells to apoptosis by ATF2.
Walczynski J, Lyons S, Jones N, Breitwieser W.
Oncogene. 2013 Feb 18. doi: 10.1038/onc.2013.28. [Epub ahead of print]
PMID: 23416976 [PubMed - as supplied by publisher]
Removal of Centrosomal PP1 by NIMA Kinase Unlocks the MPF Feedback Loop to Promote Mitotic Commitment in S. pombe.
Grallert A, Chan KY, Alonso-Nuñez ML, Madrid M, Biswas A, Alvarez-Tabarés I, Connolly Y, Tanaka K, Robertson A, Ortiz JM, Smith DL, Hagan IM.
Curr Biol. 2013 Feb 4;23(3):213-22. doi: 10.1016/j.cub.2012.12.039. Epub 2013 Jan 17.
PMID: 23333317 [PubMed - in process]